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Samuel H Wilson Selected Research

Methyl Methanesulfonate

9/2013Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses.
6/2008DNA damage response protein ASCIZ links base excision repair with immunoglobulin gene conversion.
4/2007Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiency.
9/2005Involvement of poly(ADP-ribose) polymerase activity in regulating Chk1-dependent apoptotic cell death.
9/2004Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping.
10/2003Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses.
1/2003Hypersensitivity of DNA polymerase beta null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions.

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Samuel H Wilson Research Topics

Disease

22Neoplasms (Cancer)
01/2021 - 05/2003
13Genomic Instability
01/2022 - 05/2003
10Hypersensitivity (Allergy)
12/2017 - 01/2003
4Neurodegenerative Diseases (Neurodegenerative Disease)
01/2021 - 06/2004
3Mitochondrial Diseases (Mitochondrial Disease)
12/2020 - 06/2004
3Huntington Disease (Huntington's Disease)
01/2016 - 05/2007
3Werner Syndrome (Werner's Syndrome)
01/2006 - 06/2003
2Breast Neoplasms (Breast Cancer)
01/2020 - 01/2013
2Inflammation (Inflammations)
08/2015 - 01/2010
1autosomal recessive 1 Spinocerebellar ataxia
02/2015
1Prostatic Neoplasms (Prostate Cancer)
10/2013
1Carcinogenesis
06/2010
1Stomach Neoplasms (Stomach Cancer)
11/2009
1Hyperplasia
08/2009
1Mental Disorders (Mental Disorder)
07/2008
1Dementia (Dementias)
07/2008
1Stroke (Strokes)
07/2008
1Lymphoma (Lymphomas)
07/2007
1Necrosis
09/2005
1DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes)
04/2005
1Ataxia Telangiectasia (Louis Bar Syndrome)
04/2005
1Chronic Disease (Chronic Diseases)
06/2004
1Cardiovascular Diseases (Cardiovascular Disease)
06/2004
1Brain Injuries (Brain Injury)
06/2004
1Asthma (Bronchial Asthma)
06/2004
1Chromosome Aberrations (Chromosome Abnormalities)
09/2003
1Cataract (Cataracts)
05/2003

Drug/Important Bio-Agent (IBA)

13DNA (Deoxyribonucleic Acid)IBA
01/2020 - 01/2003
10DNA Polymerase beta (DNA Polymerase IV)IBA
06/2010 - 01/2003
8DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
01/2022 - 09/2011
7Proteins (Proteins, Gene)FDA Link
09/2013 - 05/2003
7Methyl MethanesulfonateIBA
09/2013 - 01/2003
5NucleotidesIBA
01/2022 - 06/2010
5Poly(ADP-ribose) Polymerase InhibitorsIBA
08/2014 - 08/2010
3RibonucleotidesIBA
01/2021 - 09/2011
3A-Form DNA (A-DNA)IBA
01/2020 - 10/2009
3EnzymesIBA
01/2020 - 05/2007
3Alkylating AgentsIBA
08/2010 - 01/2003
2deoxyguanosine triphosphate (dGTP)IBA
01/2021 - 01/2021
2Formaldehyde (Formol)FDA Link
01/2021 - 01/2020
2Oxygen (Dioxygen)IBA
09/2017 - 06/2004
2Complement System Proteins (Complement)IBA
02/2015 - 02/2005
2Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
08/2010 - 04/2005
1Gentian Violet (Violet, Crystal)FDA Link
12/2020
1MethyltransferasesIBA
01/2020
1ChromatinIBA
01/2019
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
12/2017
1Hydroxyl RadicalIBA
09/2017
1DNA Ligase ATPIBA
09/2017
1Superoxides (Superoxide)IBA
09/2017
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
09/2017
1NitrogenIBA
09/2017
1DNA-(Apurinic or Apyrimidinic Site) Lyase (AP Endonuclease)IBA
11/2015
1IonsIBA
09/2015
1Biomarkers (Surrogate Marker)IBA
08/2015
1Hypochlorous Acid (Hypochlorite)IBA
08/2015
15-chlorocytosineIBA
08/2015
1Cell ExtractsIBA
02/2015
1Anti-Bacterial Agents (Antibiotics)IBA
01/2015
1olaparibIBA
08/2014
1veliparibIBA
08/2014
1Leucine (L-Leucine)FDA Link
04/2014
1Proline (L-Proline)FDA Link
04/2014
1LyasesIBA
04/2014
1BRCA1 ProteinIBA
01/2013
1DeoxyribonucleotidesIBA
10/2012
1gamma-fluoromethylenedeoxyguanosine triphophateIBA
06/2010
1CarbonIBA
06/2010
1HMGB1 Protein (HMG1)IBA
01/2010
1Protein Isoforms (Isoforms)IBA
11/2009
1Untranslated RNA (Noncoding RNA)IBA
11/2009
18-hydroxyguanineIBA
10/2009
1Folic Acid (Vitamin M)FDA LinkGeneric
07/2008
1HomocysteineIBA
07/2008
1Hypoxanthine Phosphoribosyltransferase (Hypoxanthine Guanine Phosphoribosyltransferase)IBA
07/2007
1Thymidine KinaseIBA
07/2007
1Temozolomide (Temodar)FDA LinkGeneric
04/2007
1Cisplatin (Platino)FDA LinkGeneric
10/2006
1Adenosine Triphosphate (ATP)IBA
09/2005
1CaspasesIBA
09/2005
1Caffeine (No Doz)FDA LinkGeneric
04/2005
1Phosphotransferases (Kinase)IBA
04/2005
14-amino-1,8-naphthalimideIBA
04/2005
1A-factor (Streptomyces)IBA
06/2004
1Uracil-DNA GlycosidaseIBA
06/2004
1Glucose (Dextrose)FDA LinkGeneric
06/2004
1CarcinogensIBA
09/2003
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
05/2003
1Doxycycline (Periostat)FDA LinkGeneric
05/2003
1DNA AdductsIBA
01/2003
1Phosphates (Orthophosphate)IBA
01/2003
13-methyladenineIBA
01/2003
1O(6)-benzylguanineIBA
01/2003

Therapy/Procedure

4Therapeutics
09/2017 - 08/2010
3Drug Therapy (Chemotherapy)
09/2013 - 04/2007
1Ligation
09/2017